Research areas
Novel ligand-gated ion channels in nerve cells.
Nerve cells communicate by releasing chemical messengers, often referred to as neurotransmitters. Some neurotransmitters exert fast effects (via ligand-gated ion channels) others slow effects (via enzyme coupled receptors). We have recently discovered fast actions of two transmitters hithertoo only thought to produce slow effects: a neuropeptide, FMRFamide, and dopamine. The channels directly gated by these substances are being studied in detail. The peptide gated channel (now cloned) is unique in showing a high selectivity for Na ions and also in being antagonised by another endogenous, related, peptide.
Selected publications
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Open access
Moult, P. R., Cottrell, G. A. & Li, W., 9 Jan 2013, In: Neuron. 77, 1, p. 129-140 12 p.
Research output: Contribution to journal › Article › peer-review
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Reece, P. J., Dholakia, K., Thomas, R. C. & Cottrell, G. A., 15 Mar 2008, In: Neuroscience Letters. 433, 3, p. 265-269 5 p.
Research output: Contribution to journal › Article › peer-review
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Reece, P. J., Dholakia, K. & Cottrell, G. A., 2007, Acta Physiologica.
Research output: Book/Report › Book
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Cottrell, G. A., Jun 2005, In: Pflügers Archiv: European Journal of Physiology. 450, 3, p. 168-177 10 p.
Research output: Contribution to journal › Article › peer-review
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Green, K. & Cottrell, G. A., Mar 2002, In: Pflügers Archiv: European Journal of Physiology. 443, 5-6, p. 813-821 9 p.
Research output: Contribution to journal › Article › peer-review
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Davey, F. D., Harris, S. & Cottrell, G. A., Nov 2001, In: Journal of Neurocytology. 30, p. 877-84 8 p.
Research output: Contribution to journal › Article › peer-review
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Cottrell, G. A., Jeziorski, M. & Green, K., 26 Jan 2001, In: FEBS Letters. 489, p. 71-74 4 p.
Research output: Contribution to journal › Article › peer-review
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Green, K. A., Powell, B. & Cottrell, G. A., Jan 2000, In: British Journal of Pharmacology. 129, 1 p.
Research output: Contribution to journal › Article › peer-review
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Cottrell, G. A., Jeziorski, M., Green, K. & Sommerville, J., 1 Jul 2000, In: The Journal of Physiology. 526, 1, p. 13-25 13 p.
Research output: Contribution to journal › Article › peer-review
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Green, K. A. & Cottrell, G. A., Sept 2000, In: The Journal of Physiology. 527, 1 p.
Research output: Contribution to journal › Article › peer-review
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