Research areas
Cytoskeletal assembly during tissue morphogenesis
Investigations deal mainly with the roles of microtubule-organizing centres during the development of certain animal tissues. Microtubule assembly during tissue morphogenesis and in reponse to experimentally induced perturbations is largely monitored using transmission electron microscopy and fluorescence microscopy in conjunction with antibodies and green fluorescent protein. Current studies are mainly concerned with control of microtubule positioning during cell differentiation in primary embryonic Drosophila cell cultures.
My studies of microtubules have involved investigations of the following fundamental cell functions, on occasion: mitosis, anaphase chromosome movement, cell division, cleavage furrow formation, cell motility, cell locomotion, cell shaping, cytoplasmic streaming, endocytosis, tissue morphogenesis, positioning of centrioles and basal bodies, organelle assembly and replication, deployment of microfilaments and intermediate filaments, cell adhesion, collagen secretion and alignment, and oogenesis
Selected publications
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Tucker, J. B., Mackie, J., Cottam, D., Rogers-Bald, M., Macintyre, J., Scarborough, J. & Milner, M. J., Mar 2004, In: Cell Motility and the Cytoskeleton. 57, 3, p. 175-185 11 p.
Research output: Contribution to journal › Article › peer-review
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Mogensen, M., Tucker, J. B., Mackie, J., Prescott, A. & Nathke, I., 10 Jun 2002, In: Journal of Cell Biology. 157, p. 1041-1048 8 p.
Research output: Contribution to journal › Article › peer-review
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Mogensen, M. M., Tucker, J. B., Mackie, J. B., Prescott, A. R. & Nathke, I. S., Nov 2001, In: Molecular Biology of the Cell. 12, 1 p.
Research output: Contribution to journal › Article › peer-review
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Tucker, J. B., Mackie, J., Bussoli, T. & Steel, K., Dec 1999, In: Journal of Neurocytology. 28, p. 1017-1034 18 p.
Research output: Contribution to journal › Article › peer-review
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Tucker, J. B., Mogensen, M., Henderson, C., Mackie, J. & 2, O., 1998, In: Cell Motility and the Cytoskeleton. 41, p. 138-153 16 p.
Research output: Contribution to journal › Article › peer-review
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Tucker, J. B., Mogensen, M., Henderson, C., Doxsey, S. & 2, O., Jan 1998, In: Journal of Anatomy. 192, p. 119-130 12 p.
Research output: Contribution to journal › Article › peer-review
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Tucker, J. B., Mogensen, M., Mackie, J., Doxsey, S. & 1, O., 1997, In: Cell Motility and the Cytoskeleton. 36, p. 276-290 15 p.
Research output: Contribution to journal › Article › peer-review
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