Research areas
Judith Sleeman is a former Royal Society University Research Fellow with key interests in the physical organisation of RNA processing in mammalian cells and the impact of this on human disease. Leading on from early work into the cellular organisation of splicing snRNP maturation, research in the Sleeman lab has expanded to include cytoplasmic transport of mRNA and the effects on cellular structure of triplet repeat disorders. Current projects in the group investigate the cellular and molecular basis of Spinal Muscular Atrophy, Myotonic Dystrophy Type 1 and Amyotrophic Lateral Sclerosis. Key techniques include live-cell and high-resolution microscopy and proteomics.
PhD supervision
- SophieÌýCuthbertson
Selected publications
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Open access
Gulyurtlu, S., Magon, M. S., Guest, P. N., Papavasiliou, P. P., Morrison, K., Prescott, A. & Sleeman, J. E., 2 Aug 2022, In: Disease Models & Mechanisms. 15, 7, dmm049294.
Research output: Contribution to journal › Article › peer-review
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Open access
Sleeman, J. E., 19 Jul 2021, The Conversation.
Research output: Contribution to specialist publication › Article
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Open access
Thompson, L. W., Morrison, K. D., Shirran, S. L., Groen, E. J. N., Gillingwater, T. H., Botting, C. H. & Sleeman, J. E., 17 Apr 2018, In: Journal of Cell Science. 131, 8, 18 p., jcs211482.
Research output: Contribution to journal › Article › peer-review
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Open access
Trinkle-Mulcahy, L. & Sleeman, J. E., 2017, In: RNA Biology. 14, 6, p. 739-751
Research output: Contribution to journal › Review article › peer-review
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Sleeman, J. E. & Trinkle-Mulcahy, L., Jun 2014, In: Current Opinion in Cell Biology. 28, p. 76-83 8 p.
Research output: Contribution to journal › Article › peer-review
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Open access
Prescott, A. R., Bales, A., James, J., Trinkle-Mulcahy, L. & Sleeman, J. E., 14 Feb 2014, In: Journal of Cell Science. 127, 4, p. 812-827 15 p.
Research output: Contribution to journal › Article › peer-review
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Open access
Coleman, S., Prescott, A. R. & Sleeman, J. E., 1 Mar 2014, In: Biochemical Journal. 458, 2, p. 267-280 13 p.
Research output: Contribution to journal › Article › peer-review
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Sleeman, J., Aug 2013, In: Biochemical Society Transactions. 41, 4, p. 871-875 5 p.
Research output: Contribution to journal › Article › peer-review
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Open access
Clelland, A. K., Bales, A. B. E. & Sleeman, J. E., 1 Jun 2012, In: Journal of Cell Science. 125, 11, p. 2626-2637 12 p.
Research output: Contribution to journal › Article › peer-review
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Open access
Clelland, A. K., Kinnear, N. P., Oram, L., Burza, J. & Sleeman, J. E., Nov 2009, In: Traffic. 10, 11, p. 1585-1598 14 p.
Research output: Contribution to journal › Article › peer-review
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