Research areas
Molecular genetics of human breast cancer
Research concentrates on the phenomenon of familial cancers, particularly of the breast. It includes: participation in 'cancer family' clinics in Dundee and Edinburgh for assessment of risk to members of such families, investigation of interactions between genetic and environmental risk factors, and evaluation of screening and intervention strategies. Laboratory work concentrates on characterisation of mutations predisposing to breast and other cancers, particularly in the BRCA 1 and BRCA 2 genes. Questions addressed include: the frequencies of specific mutations in the Scottish population, (compared with others throughout the world), the clinical consequences of particular mutations, and the biochemical/cellular effects of gene inactivation or alteration.
Selected publications
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Hanning, K., Steel, C. M., Goudie, D., McLeish, L., Dunlop, J., Myring, J., Sullivan, F., Berg, J., Humphris, G. M. & Ozakinci, G., Oct 2015, In: Health Expectations. 18, 5, p. 1735-1743
Research output: Contribution to journal › Article › peer-review
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Gilmour, A., Ritchie, M. R., Mackinnon, L. J., Wong, V., Charlton, C., Steel, C. M., Gates, S. E. E., Smith, J. & Gibbs, T. J., 2007, In: Proceedings of the Nutrition Society . 66, p. 31A-31A 1 p.
Research output: Contribution to journal › Article › peer-review
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Open access
Ozakinci, G., Humphris, G. & Steel, M., Dec 2007, In: Community Genetics. 10, 1, p. 41-44 4 p.
Research output: Contribution to journal › Article › peer-review
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Moller, P., Evans, D., Reis, M., Gregory, H., Anderson, E., Maehle, L., Lalloo, F., Howell, A., Apold, J., Clark, N., Lucassen, A. & Steel, C. M., 1 Sept 2007, In: International Journal of Cancer. 121, 5, p. 1017-1020 4 p.
Research output: Contribution to journal › Article › peer-review
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Reis, M. M., Young, D., McLeish, L., Goudie, D., Cook, A., Sullivan, F., Vysny, H., Fordyce, A., Black, R., Tavakoli, M. & Steel, M., Nov 2006, In: Familial Cancer. 5, 4, p. 297-303 7 p.
Research output: Contribution to journal › Article › peer-review
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Ritchie, M. R., Cummings, J. H., Morton, M. S., Steel, C. M., Bolton-Smith, C. & Riches, A. C., Jan 2006, In: British Journal of Nutrition. 95, p. 204-213 10 p.
Research output: Contribution to journal › Article › peer-review
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Young, D., McLeish, L., Sullivan, F., Pitkethly, M., Reis, M., Goudie, D., Vysny, H., Ozakinci, G. & Steel, M., 23 Oct 2006, In: British Journal of Cancer. 95, 8, p. 974-978 5 p.
Research output: Contribution to journal › Article › peer-review
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Warren, R. M. L., Pointon, L., Thompson, D., Hoff, R., Gilbert, F. J., Padhani, A., Easton, D., Lakhani, S. R., Leach, M. O., Steel, M. & MARIBS Study Grp, Sept 2005, In: Radiology. 236, 3, p. 779-788 10 p.
Research output: Contribution to journal › Article › peer-review
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Stirling, D., Evans, D. G. R., Pichert, G., Shenton, A., Kirk, E. N., Rimmer, S., Steel, C. M., Lawson, S., Busby-Earle, R. M. C., Walker, J., Lalloo, F., Eccles, D. M., Lucassen, A. M. & Porteous, M. E., 20 Aug 2005, In: Journal of Clinical Oncology. 23, 24, p. 5588-5596 9 p.
Research output: Contribution to journal › Article › peer-review
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McCallum, M., Baker, C., Gillespie, K., Cohen, B., Stewart, H., Leonard, R., Cameron, D., Leake, R., Paxton, J., Robertson, A., Purdie, C., Gould, A. & Steel, M., 17 May 2004, In: British Journal of Cancer. 90, p. 1933-1941 9 p.
Research output: Contribution to journal › Article › peer-review